Pure Natural Dendrobium Extract 80 Mesh Dendrobine 10% CAS 2115-91-5

Product Description

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What is Dendrobium Extract?

Dendrobium extract, also named dendrobium nobile extract, Shi Hu in Chinese, has been used as a traditional herb medicine in China for more than 1300 years. From wikipedia,There are many dendrobium species available, such as dendrobium nobile Lindl, dendrobium candidum, dendrobium officinale, dendrobium huoshanense, and dendrobium devonianum Paxt. However, among these species, dendrobium nobile is the most common and popular extract.

Dendrobium is an excellent and delicious Yin Jing tonic and longevity herb. It is said to quickly and effectively replace spent "adaptive energy." It is widely used in the Orient by those who engage in a lot of marital activity to replace the spent energy and to replace fluids; and thus it is commonly called "honeymooners tea."

Dendrobium is primarily used in China to replenish fluids. It is commonly used in Chinese herbalism as a Yin tonic which moistens the Stomach and Lungs. It can be very effective in treating dryness problems like dry mouth, thirst, stomach pain, mouth sores, sunstroke, and dry lungs and air passages due to dry weather or due to pollution and smoke. In other words, Dendrobium is used to balance hot, dry conditions, to replace damaged or lost fluids and to relieve thirst, depression and deficiency fever as a result an illness. Dendrobium also helps to generate beautiful skin.

Dendrobium is a member of the orchid (Orchidaceae) family and has been used in traditional Chinese medicine for many centuries to treat thirst, fever, diabetes, infection, inflammation, cancer, protect eyesight, and improve appetite and digestion. Dendrobium is now an ingredient in some pre-workout dietary supplements marketed to enhance physical or athletic performance.

What is Dendrobine?

Dendrobine has analgesic and antipyretic effects, can reduce heart rate, blood pressure, slow breathing, has a strong effect and can relieve barbiturate poisoning. Pharmacological tests show that oral decoction of dendrobium can promote the secretion of Chemicalbook gastric juice to aid digestion, make intestinal peristalsis hyperactive and laxative, but if the dose is too large, it can lead to paralysis of intestinal muscles; dendrobine has certain antipyretic and analgesic effects , similar to phenacetin.

pharmacological action:

1.boost immunity

Pharmacological studies have shown that Dendrobium can be used for nonspecific immunity and specific immunity.

It can effectively improve the immunity of the body, and its the immune activity is affected by its chemical composition, molecular conformation, relative molecular mass, glycosidic bond and many other factors. Dendrobium officinale polysaccharide can induce induce macrophages to secrete tumor necrosis factor-α (TNF-α) Strong phagocytosis of macrophages, thereby enhancing innate immune defense use. Li et al. found that the polysaccharide DHP-4A of Dendrobium Activates p38, JNK, extracellular regulated protein kinase (ERK), nuclear Transcription factor-κB (NF-κB) signaling pathway to promote macrophages RAW 264.7 secretes NO, TNF-α, interleukin-6 (IL-6), IL-10 plays an immunomodulatory role.

2 Relief of diabetes and its complications

Diabetes is a disease caused by lack of insulin, insulin resistance Metabolic diseases caused by retinopathy, leukemia Complications such as cataracts, neuropathy, kidney disease, and cardiovascular disease. Stone The mechanism of action of dendrobium in the treatment of type 2 diabetes and its complications mainly includes:

Protect islet cells, reduce insulin resistance, promote glucose dependence Sexual insulin-releasing peptide (GIP) secretion, correction of lipid metabolism disorder disorder and inhibition of calcium ion channels.

3 Anti-tumor

The use of Dendrobium officinale methanol extract (DCME) for in vivo, in vitro anticancer activity experiments, the results show that DCME inhibits colon cancer growth of HCT-116 cells, causing apoptosis; upregulated by bax, caspase-9, caspase-3 and down-regulated Bcl-2, iNOS, NF-κB and cyclooxygenase-2 (COX-2) expression, which play a role in promoting apoptosis and anti-inflammatory effects; pass through in mouse colon 26-M3.1 cells by inhibiting MMP gene expression and promoting TIMPs gene expression, play a role in inhibiting tumor metastasis.

4 Antioxidant and anti-aging

At present, it is generally believed that oxidative stress is closely related to aging, neuropathy, diabetes, cardiovascular disease and cancer, and various antioxidants and free radical scavengers isolated from Dendrobium can be of great help in the treatment of such diseases. Dendrobium officinale powder aqueous suspension (DO), crude polysaccharide (c-DOP), pure polysaccharide (p-DOP) can make superoxide dismutase (SOD), glutathione peroxide in mouse serum, thymus and liver The activity of enzyme (GSH-Px) and catalase (CAT) increased, and the level of malondialdehyde (MDA) decreased, indicating that Dendrobium has antioxidant effect. Dendrobium officinale water-soluble polysaccharide (DOP) can scavenge DPPH free radicals well, exhibit high scavenging activity against hydroxyl radicals, and high metal chelating activity, indicating that Dendrobium officinale polysaccharide may be an effective natural antioxidant. Wu et al. [65] found that Dendrobium officinale polysaccharides could protect mitochondria in ovaries of naturally aging mice by inhibiting NF-κB and p53/Bcl-2-mediated signaling pathways, and alleviate ovarian aging damage.

5 Liver protection

Monoketene (MFD), a phenanthrenediquinone in D. moniliforme (L.) Sw., can reduce the phosphorylation level of p65 NF-κB in rat hepatic stellate cells HSC-T6 , significantly down-regulated aspartate aminotransferase (AST), lactose dehydrogenase (LDH), liver hydroxyproline, α-smooth muscle actin (α-SMA), collagen type I (COL-1 ) expression level, alleviate liver inflammation, necrosis and fibrosis caused by CCl4, by inhibiting NF-κB signaling pathway and down-regulating transforming growth factor (TGF-β1) and its downstream α-SMA, COL-1, connective tissue growth factor ( The expression level of CTGF inactivates hepatic stellate cells (HSCs), thereby exerting an anti-fibrotic effect.

6 Anti-inflammatory effects

Inflammation is closely related to many chronic diseases and has become a research hotspot in recent years. Ge et al. found that Dendrobium huoshanense polysaccharides can resist cigarette smoke-induced lung inflammation by regulating NF-κB and mitogen-activated protein kinase (MAPK) signaling pathways.

7 Others

Dendrobium also has pharmacological effects such as improving gastrointestinal function, anti-angiogenesis, improving allergic dermatitis, relieving fatigue, anti-platelet aggregation, bacteriostasis, and anti-mutagenesis. Acetyl-rich polysaccharides can increase the content of colonic short-chain fatty acids (SCFAs), colon length and index, and fecal moisture in mice, while the colonic pH decreases and defecation time is shortened, which is conducive to fermentation and regulation of the colonic microenvironment, thereby promoting to maintain colon health.

With the continuous in-depth research on Dendrobium, it is found that Dendrobium contains rich active ingredients, such as polysaccharides, alkaloids, flavonoids, phenols, terpenes, etc. Through the analysis of its active components, the content of each component in Dendrobium and their respective chemical structures were determined. Activity studies have found that Dendrobium mainly has the activities of enhancing immunity, inhibiting tumors, anti-oxidation, and anti-inflammatory. At the same time, Dendrobium can be used in combination with other treatment methods to treat clinical diseases, which has the advantages of significant curative effect and small side effects. Therefore, the research on the application value of Dendrobium as a health product and medicine has been paid more and more attention, and related research reports have also shown a trend of rapid growth.

Application

1, Dendrobium is used in herbal remedies.In traditional Chinese medicine

2, Dendrobium is used primarily to replenish fluids

3, Dendrobium is used as a yin tonic to moisten the stomach and lungs

4, Dendrobium is used as a tea to replace kidney yin jing

5, Dendrobium is very effective for treating conditions such as dry mouth, stomach pain, mouth sores,

sunstroke, and other conditions caused by dry weather, pollution or smoke.Additionally

6, Dendrobium is used to enhance skin quality. Dendrobium keeps the skin moist; constant drinking of

dendrobium tea is believed to result in soft, beautiful skin

7, Dendrobium is used in Chinese Medicine for stomach ailments, and to promote the production of body fluid, and to reduce body heat.