Dihydromyricetin 98% Organic Vine Tea Extract CAS 27200-12-0

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Vine Tea Extract

The Vine tea plant is one kind of rare typical tea plant, young stem and leaf from Ampelopsis gross dental, a plant growing in 1300-1950m hillside shrub or valley woodland, always used as a legendary healthy tea. Researches show that vine tea can relieve inflammation, mixture cough, and antitussives. It also has a strong inhibitory effect on common bacteria in food.

“Chinese Herbal Medicine Collection” wrote that the vine tea (Teng Cha ) has a glycol flavor, the nature is cool; It can alleviate fevers and drunken, cure rheumatism, strengthen physique and many other functions. The vine tea (Teng Cha) contains rich flavonoids, amino acids, vitamins, proteins, and essential trace elements, in which the content of total flavones and Dihydromyricetin elements are incredibly high.

Dihydromyricetin (DHM) is a natural extract of the vine tea plant. DHM has been used for centuries in traditional Chinese medicine as a hangover cure and intoxication blocker.

What is Hydromyricetin?

Hydromyricetin is the extract of grape vine tea, and it is the main active component of flavonoids in vine tea. These substances have many peculiar effects such as scavenging free radicals, anti-oxidation, anti-thrombosis, anti-tumor, anti-inflammatory, etc.; Dihydromyricetin is a special kind of flavonoids, which can relieve alcohol poisoning, prevent alcoholic liver, fatty liver, inhibit the deterioration of liver cells, reduce the incidence of liver cancer, resist hypertension, inhibit platelet aggregation in vitro and thrombosis in vivo It has special effects in reducing blood lipid and blood sugar levels, improving SOD activity and protecting liver. It can also be used in feed as an antioxidant, controlling E.coli, aflatoxin, and mold. In addition, it helps improve the taste and flavors of poultry meat.

Antibacterial effect: Pharmacological experiments show that dihydromyricetin has antibacterial effects on Bacillus subtilis, Staphylococcus aureus, Salmonella, Escherichia coli, Aerobacter, Saccharomyces cerevisiae, Rhodotorula, Penicillium, Aspergillus niger, Aspergillus flavus, Trichoderma Mold and Rhizopus have bacteriostatic effect, especially on Gram-positive, Gram-negative cocci or bacilli.

Regulating effect on blood sugar and blood lipids: Pharmacological experiments of mouse gavage show that dihydromyricetin can significantly inhibit the rise of blood sugar in mice induced by alloxan, epinephrine, streptozotocin, etc., and at the same time increase serum insulin levels, The infiltration of lymphocytes in pancreatic tissue was significantly reduced, the inflammatory response was significantly reduced, and the number of pancreatic islets was significantly increased. Dihydromyricetin can reduce the content of serum triacylglycerol (TG) in streptozotocin-induced hyperglycemia rats, but has no significant effect on the content of serum total cholesterol (TC) and high density lipoprotein cholesterol (HDL2C).

Hepatoprotective effect: Dihydromyricetin has significant protective effect on rat hepatocytes from carbon tetrachloride poisoning injury, D2 galactosamine and lipopolysaccharide-induced liver injury in mice. Dihydromyricetin can protect the liver, accelerate the rapid decomposition of acetaldehyde, a metabolite of ethanol, and turn it into a non-toxic substance, reducing its damage to liver cells. In addition, dihydromyricetin can improve the increase of serum lactate dehydrogenase activity caused by liver cell injury, inhibit the formation of collagen fibers in hepatic M cells, so as to protect the liver and protect the liver, and greatly reduce the damage of ethanol to the liver. The normal state of the liver can be quickly restored. Microherb test proves that dihydromyricetin can protect the liver, accelerate the rapid decomposition of acetaldehyde, a metabolite of ethanol, into non-toxic substances, and reduce damage to liver cells. Dihydromyricetin works quickly and has a long-lasting effect.

Antioxidative effect: Dihydromyricetin with a purity of 98% can significantly inhibit the formation of malondialdehyde (MDA) in rat myocardial, liver and brain tissue homogenates, and inhibit the formation of MDA with the increase of dihydromyricetin concentration. The effect was increased, the scavenging rate of diphenyltrinitrophenylhydrazine (DPPH) free radicals in the test system with 99% dihydromyricetin. Dihydromyricetin can significantly inhibit the formation of MDA in oil, and the antioxidant effect is enhanced with the increase of dihydromyricetin purity (60% to 90%); it has strong antioxidant effect on animal and vegetable oils.

Anti-tumor effect: In recent years, anti-tumor pharmacodynamics studies have found that one of its active ingredients, the small molecule compound of rhodopsin, has a relatively strong anti-cancer effect. In vitro and in vivo anti-tumor studies have found that the compound can improve tumor treatment effects and improve patients' vital symptoms by inhibiting tumor blood vessel growth, regulating and enhancing cellular immune function, etc. showed significant tumor suppressor effect.

Application:

The Vine tea extract (Dihydromyricetin) is a flavonoid with high bioactivity that treats liver diseases, hangovers, and vascular sclerosis. It’s also used as an antioxidant and anti-inflammatory substance. It’s been widely used as antioxidants and preservatives in food, effective in reducing free radicals, inflammation, and lipids, relieving cough, and protecting your liver. It’s been applied to various industries: healthcare products, personal care products, food additives, and feed supplements, which help boost immunity, improve average daily gain, feed intake, and feed efficiency.

1) Liver Protection

The Vine tea extract (Dihydromyricetin) has a strong inhibitory action of increasing ALT and AST in the blood Serum. It can lower the total bilirubin in the blood serum. So it has the vital function of lowing the aminotransferase and jaundice and can restrain liver fibrosis in the rat. It helps recovery from drunk and dramatically reduces hangover symptoms. They are widely used in medicine preparation of respiratory tract infection and alcohol intoxication.

The Vine tea extract (Dihydromyricetin) doesn’t just prevent you from getting drunk but can sober you up after a night of drinking. It does this in two primary ways:

It blocks alcohol’s effect on your GABAa receptors, preventing the increased impact of GABA from causing the negative symptoms commonly associated with drunkenness.

It causes the liver to metabolize alcohol more quickly, lowering your BAC and causing you to be fully sober more quickly.

Vine tea extract (Dihydromyricetin) is currently the most effective hangover cure on the market. When combined with the age-old advice of staying hydrated, it will prevent hangovers in almost everyone.

Vine tea extract (Dihydromyricetin) isn’t just valuable and counteracting intoxication or preventing hangovers but also helps to reduce the liver toxicity caused by alcohol consumption. It also restrains the absorption of alcohol in the gastrointestinal tract, causing less of the alcohol you consume to reach your brain in the first place.

2) Protects the Brain from Oxidative Stress

The vine tea extract is well established that consuming alcohol contributes to higher levels of oxidative stress in the brain. Luckily research has identified dihydromyricetin as a potent anti-oxidant. Therefore, taking dihydromyricetin after a night of drinking is an excellent way to offset the increases in oxidative stress caused by alcohol consumption.

3) Helps Mitigate Alcohol Withdrawal

One of the most exciting finds of recent research on vine tea extract is that it may potentially treat alcoholism by lowering the desire to drink. While more research is needed to confirm if it will be helpful, a recent study has shown that DHM counteracts signs of alcohol withdrawal, including tolerance, increased anxiety, and susceptibility to seizures.

4) Clearing the free radical in the body and antioxidation

The vine tea extract can effectively level down lipid peroxidation. It can prevent the oxidative damage of antioxidase in the body caused by the free radical. Then it can improve the oxidation resistance of the human body. Used in food anti-oxidant and preservatives.

5) Antibiotic Function

The vine tea extract has the strong inhibitory action of staphylococcus aureus, Bacillus subtilis, Aspergillus flavors, penicillium, Staphylococcus aureus, Staphylococcus aureus, and Pseudomonas aeruginosa.

6) Reducing the levels of blood sugar and blood fat

The vine tea extract (Dihydromyricetin) can reduce the fat blood levels in the mouse. It can decrease the damage to liver cells caused by the high blood fat levels and improve the antioxidation ability. At the same time, it can lower the levels of high blood sugar.

7) Anti-inflammation

The vine tea extract can effectively restrain the mouse pinna swelling caused by xylene. It can also control the writhing response in the mouse caused by acetic acid.