CAS 3081-61-6 98% L-Theanine EGCG Green Tea Extract Tea Polyphenols Powder
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|Minimum Order Quantity :||25KG||Packaging Details :||Sample：1kg/bag with Polyethylene bag. Orders: Professional Drum with Net Weight 25kg|
|Delivery Time :||7-15 days||Payment Terms :||L/C, T/T|
|Supply Ability :||1000kg per month|
|Place of Origin:||CHINA||Brand Name:||HONGDA|
|Form:||Powder||Appearance:||White Fine Powder|
|Product Name:||L-Carnitine||Test Method:||HPLC|
|Application:||Food Field; Health-care Products, Pharmaceutical Products||Specification:||97.0% ~103.0%|
|Shelf Life:||2 Years||Color:||White|
L-Carnitine White Fine Powder,
CAS 541-15-1 L-Carnitine Powder,
0.7g/ml L-Carnitine Powder
|Color:||White Fine Powder|
|Particle Size:||100% pass 80 mesh|
|Loss on drying:||≤5.00%|
|Acid insoluble Ash:||≤5.0%|
|Heavy metals(as Pb):||≤10ppm|
|Total microbacterial count:||NMT10000cfu/g|
|Total Yeast & Mold:||NMT1000cfu/g|
L-carnitine, the chemical formula is C7H15NO3, the chemical name is (R)-3-carboxy-2-hydroxy-N,N,N-trimethylpropylammonium The internal salt of hydroxide, the representative drug is L-carnitine. It is a kind of amino acid that promotes the conversion of fat into energy. The pure product is white crystal or white transparent fine powder. It is easily soluble in water, ethanol and methanol, slightly soluble in acetone, and insoluble in ether, benzene, chloroform and ethyl acetate. ester. L-carnitine is easy to absorb moisture, has good water solubility and water absorption, and can withstand high temperatures above 200 °C. It has no toxic and side effects on the human body. Red meat is the main source of L-carnitine, and the human body can also synthesize it to meet physiological needs. Not a real vitamin, just a vitamin-like substance. It has many physiological functions such as fat oxidation and decomposition, weight loss, anti-fatigue, etc. As a food additive, it is widely used in infant food, diet food, athlete food, nutritional supplements for middle-aged and elderly people, nutritional fortifiers for vegetarians and animal feeds additives, etc.
In organism, the basic function of L-carnitine is to promote fatty acid oxidation for energy. The metabolic process of fat goes through the mitochondrial membrane. Mitochondria can metabolize fat to release energy and be consumed by the body, but long-chain fatty acids cannot pass this obstacle. L-carnitine is an essential coenzyme in fat metabolism, which can promote fatty acids to enter mitochondria for oxidative decomposition, and is a carrier for transporting fatty acids. As a key substance in fatty acid β-oxidation and TCA cycle, L-carnitine can transfer excess fatty acid and other fatty acid residues in the body in the form of ester acyl from outside the mitochondrial membrane to the inside of the membrane, so as to balance the energy in the cell. Since L-carnitine can promote fatty acids to pass through the mitochondrial membrane for oxidative energy supply, it can promote the burning of body fat to provide energy during exercise, and can also convert fatty acids, branched-chain amino acids (leucine, isoleucine) and valine) and the common product of glucose oxidation, acetyl coenzyme A, passes through the cell membrane in the form of acetyl carnitine, promotes the oxidation and utilization of acetoacetate, and plays a role in the elimination and utilization of ketone bodies, so it has three major functions in the body. The function of energy nutrient oxidation.
Carnitine can promote the activity of intracellular pyruvate dehydrogenase, thereby promoting the oxidation of glucose, which is beneficial to delay the occurrence of fatigue during exercise. Excessive production of lactic acid during exercise will increase the acidity of blood tissue fluid, reduce the production of ATP, and lead to fatigue. L-carnitine supplementation can remove excess lactic acid, improve exercise ability, and promote the recovery of exercise-induced fatigue.
In addition, it can also be used as a biological antioxidant to scavenge free radicals and promote the urea cycle. Ammonia is a product of protein degradation and one of the identifying signs of exercise-induced fatigue, and even lower levels of ammonia are more toxic. L-carnitine can degrade ammonia into urea, thereby detoxifying ammonia.
L-carnitine protects the stability of cell membranes, improves the body's immunity, avoids the invasion of some diseases, and plays a preventive role in the prevention and treatment of sub-health.
Energy is the greatest anti-aging force, and cells will be full of energy if they have enough energy. In the process of human aging, the weakening of cell energy is one of the reasons for accelerated aging. Proper supplementation of L-carnitine can delay the aging process.
L-carnitine has certain functions in maintaining the life of infants and promoting certain physiological processes of infant development, such as ketosis and ammonia metabolism. Adults can synthesize the concentration of L-carnitine required to maintain normal metabolism by themselves, but infants' L-carnitine synthesis ability is weak, only 12-15% of adults, especially premature infants. L-carnitine is an essential nutrient for conditional infants. Babies play an important role in their metabolism using fat as an energy source.
The heart is the most "hard-working" organ in the human body, and it needs to pump blood continuously to maintain human life. At least 2/3 of the energy source of the constantly moving heart cells comes from the oxidation of fat, and L-carnitine is an indispensable key substance for fat oxidation, which is beneficial to the health of the heart and blood vessels.
L-carnitine is extremely important for the health of cardiomyocytes. Supplementing enough L-carnitine can help improve heart function in people with congestive heart problems, minimize its damage after a heart attack, reduce the pain of angina, and improve Arrhythmia without affecting blood pressure.
In addition, L-carnitine can also increase the level of high-density lipoprotein in the blood, help to remove cholesterol from the body, protect blood vessels, reduce blood lipids, and also reduce blood pressure in patients with hypertension.
Studies have shown that it also has a certain effect on the absorption of calcium and phosphorus.
L-carnitine has certain functions in maintaining the life of infants and promoting certain physiological processes of infant development. Adults can synthesize the concentration of L-carnitine needed to maintain normal metabolism by themselves, but infants' L-carnitine synthesis ability is weak, only 12-15% of adults, especially premature infants, cannot meet their normal metabolic needs, and infants grow and develop rapidly. The required carnitine has increased sharply. For infants, carnitine has become a conditionally essential nutrient. Appropriate supplementation of exogenous carnitine is beneficial to the normal growth and development of infants. L-carnitine content in breast milk is high, and infants mainly rely on breast milk to supply the required L-carnitine. Under normal circumstances, it can meet the needs of the baby's body. However, with the change of social environment, many mothers cannot breastfeed their infants due to insufficient lactation, going out to work and other reasons, and artificially feed their infants with commercially available formula.
There are 4 main types of infant formula:
①Milk-based formula food;
②Milk and whey protein-based formula food;
③ Soybean-based formula food;
④Protein decomposition product-based formula food.
①②The content of carnitine in the formula is higher, while the content of carnitine in the formula ③④ is far lower than that of human milk.
The levels of fortified carnitine in many types of soy formulas vary, and excesses have also occurred. But fortified carnitine is not the more the better, it can meet the needs of the baby, too much will increase the burden on the baby's kidneys, causing unnecessary waste and harm.
Weight loss pills
In the 1970s, it was reported that carnitine was used to treat obesity and lose weight. L-carnitine is an excellent weight loss active substance and a normal component of diet. Its main function is to help long-chain fatty acids to carry out β-oxidation of fatty acids, which is conducive to the utilization of fat by the human body, including burning excess fat. The fat is used as energy, and has no side effects on the body. At the same time, pay attention to strengthening exercise, consume the accumulated fat in the body, and play a role in losing weight. It belongs to a weight loss method that does not require dieting, anorexia, fatigue, and diarrhea. Relevant experimental results show that under the maintenance of the original living and eating habits, L-carnitine is taken continuously for 35 days in accordance with the prescribed dose of health care products, and the results show that the subject's body weight, waist circumference, hip circumference, total body fat, and subcutaneous fat thickness at each point. There was no decrease in the exercise tolerance of the subjects after the test, and no abnormality was found in the clinical symptoms of the subjects before and after the test.
After physical activity, the concentration of free carnitine in human muscle tissue decreases by about 20%, which can be improved by supplementing exogenous L-carnitine. L-carnitine is a carrier for free fatty acids to enter mitochondria. L-carnitine supplementation can increase the oxidation of free fatty acids to save the utilization of muscle glycogen, which is further reasoned to improve aerobic capacity. Studies have reported that L-carnitine can also activate the activity of pyruvate dehydrogenase by reducing the ratio of acetyl CoA/CoA, promote pyruvate oxidation, and reduce lactic acid accumulation, thereby improving the continuous ability of anaerobic exercise, promoting pyruvate oxidation, reducing Lactic acid builds up, thereby improving the ability to sustain anaerobic exercise. L-carnitine also promotes the oxidation of acetoacetate and may play a role in ketone body utilization. L-carnitine can improve the tolerance of patients with disease in exercise, such as exercise time, maximum oxygen absorption and lactate threshold and other indicators. But whether carnitine supplementation actually improves exercise performance has been inconsistent. Early studies suggest that 2-4 g/d carnitine supplementation can directly reduce respiratory quotient to prolong exercise time and increase critical exercise intensity. The recommended dose is 2 g/d. Large doses can cause diarrhea, and personal use should be careful not to contain D-carnitine. Excessive D-carnitine in tissues may replace active L-carnitine and cause muscle atrophy. However, on the other hand, there are reports in the literature that L-carnitine promotes the oxidation of pyruvate, which can accelerate the decomposition of carbohydrates, resulting in rapid consumption of muscle glycogen, which has a reducing effect on exercise capacity.
L-carnitine is an important nutritional supplement for middle-aged and elderly people. Myocardial energy comes from the oxidation of fatty acids. As an important nutrient for myocardium, L-carnitine can increase myocardial capacity and lead to an increase in cardiac blood output, so it has obvious effects on the heart. Protective effects. With the increase of age, the content of L-carnitine in the body of middle-aged and elderly people decreases continuously, which leads to the decrease of myocardial cell vitality. Therefore, it is necessary to supplement L-carnitine to facilitate the enhancement of myocardial capacity. People with diabetes and people with renal disease excrete too much urine, and the consumption of L-carnitine in the body is large, which cannot meet the needs of their own synthesis, which can easily lead to L-carnitine deficiency. Long-term supplementation of L-carnitine is required to meet the body's needs. need.
The liver is an important metabolic organ for lipids and fats. In addition to eating too much fat, which can lead to fatty liver, when the body lacks L-carnitine or the methyl supply is insufficient, it will cause long-chain fatty acid oxidation disorders, and it will also lead to fat accumulation in the liver. Fatty liver occurs due to excessive accumulation.
L-carnitine can promote the metabolism of harmful substances: L-carnitine can increase the oxidation of fatty acids for energy supply, reduce the anaerobic glycolysis of muscle glycogen, inhibit the production of lactic acid, and accelerate the elimination of lactic acid accumulated during exercise. Carnitine also participates in the metabolic transport of branched-chain acyl groups. In addition, it can scavenge free radicals, promote the urea cycle, etc.
Carnitine is the main component of the drug L-carnitine. It can be used to regulate hemorrhagic shock clinically. In addition to the vasomotor dysfunction caused by endocrine disorders under stress, the mechanism of hemorrhagic shock is also closely related to the increase of free radical content and cell damage in the body caused by ischemia and hypoxia. . In addition, during hemodialysis, because the relative molecular mass of L-carnitine is relatively small, and it is easily soluble in water, it is not easy to combine with plasma proteins. In dialysis patients with chronic renal failure, due to less dietary intake, endogenous Not much synthesis, coupled with hemodialysis clearance, can reduce the plasma free carnitine concentration by 70%. More than 90% of uremia patients on dialysis for three months have carnitine deficiency, and it is necessary to supplement L-carnitine with drugs to relieve adverse symptoms.
In animal feed, L-carnitine is widely used as a non-nutritive additive in a variety of animal breeding. Practice has found that in aquaculture, L-carnitine can increase the weight gain rate of aquatic animals; increase the reproduction rate of fish; reduce the body fat of aquatic animals, improve meat quality; save feed protein, reduce the bait coefficient, and improve the survival of aquatic animals In terms of poultry, it can significantly improve broiler growth and laying hen performance, improve feed conversion efficiency, and reduce mortality; in piglet growth, L-carnitine can significantly improve piglet body weight, daily gain and feed conversion efficiency. The suitable addition level of 50 mg/kg was 50 mg/kg, and the economic benefit of feeding increased by 33.82% after addition.