Chinese Medicine Scutellaria Baicalensis Extract 85% Baicalin CAS 21967-41-9

Product Description

Scutellaria Baicalensis Extract

This product is a light yellow powder made from Scutellaria baicalensis Georgi after extraction and drying; It has slight air and bitter taste. It can be used in both medicine and cosmetics, and is a good raw material for functional beauty cosmetics.

Baicalin (baicalin) is a kind of flavonoid compound extracted from the dry root of dicyledonous Labiatae plant Scutellaria baicalin (Scutellaria baicalensis Georgi). It is light yellow powder at normal temperature and tastes bitter. Insoluble in methanol, ethanol, acetone, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in hot acetic acid. Met ferric chloride explicit Green, met lead acetate generated orange of precipitation. Soluble in alkali and ammonia water, it begins to turn yellow, and soon turns black Brown. It has remarkable biological activity, and has antibacterial, diuretic, anti-inflammatory, lowering cholesterol, antithrombotic formation, relieving asthma, purging fire and detoxification, hemostasis, fetal safety, antiallergic reaction and spasmolysis effects, it is also a specific inhibitor of mammalian liver saliva enzyme, which has the function of regulating some diseases and has strong physiological efficacy of anti-cancer reaction.

Chinese name: baicalin
Chinese alias: baijialing; Baicalin; Baijialing, baicalin; Baicalin; Huangling glycoside;
English name: baicalin
English alias: BAICALIN;Baicaloside;5, glycoβ-d-glucopyranosiduronic Acid;baicalein 7-o-glucurinic; Baicalein 7-o-β-d-glucurinic;
CAS No.: 21967-41-9
Molecular formula: C21H18O11
Molecular weight: 446.36100

Density: 1.737g/cm3
Melting Point: 231-233°C(lit.)
Boiling Point: 836.6 ° Cat 760 mmHg
Flash point: 297.2°C
Refractive index: 1.739
Steam pressure: 1.07 E-29mmHg at 25°C

Yellow needle crystals. It is relatively stable under the condition of dilute acid, for example, hydrolysis will not occur in 2% sulfuric acid aqueous solution, but the concentration of acid increases, and the temperature rises to 110℃, it can be hydrolyzed to produce glucuronic acid and baicalin (baicalin).
Ultraviolet absorption spectrum: 280,316
Solubility is soluble in alkaline solution, but insoluble in ethanol.

Main values of Scutellaria Baicalensis Extract 85% Baicalin:

1. Anti-tumor effect
2. Anti-pathogen effect
3. Protective effect on liver injury
4. Improvement of diabetic nephropathy
5. Repair and protection of brain injury
6. Impact on retinopathy
7. Antiallergic reaction

Flowchart of Scutellaria Baicalensis Extract 85% Baicalin:

Boil Scutellaria baicalensis into 12 times (8 times) hot water for 30 minutes, combine the decoction twice, adjust pH l ~ 2 with hydrochloric acid, keep warm at 80℃ for 30 minutes, place, filter, collect the precipitates and wash them 2~3 times with 95% ethanol. Filtrate and dry at 60℃ to obtain the crude baicalin. Suspension the crude product into 10 times of water, adjust the pH value of 40% sodium hydroxide to 6.5-7.0, add activated carbon, keep the temperature at 80℃ for 30 minutes, add the same amount of ethanol, filter, and use salt for filtrate
Acid PH l ~ 2. Keep the temperature at 80℃ for 30 minutes, leave it for more than 10 hours, pour out the upper liquid, wash the precipitate with ethanol for 2~3 times, filter, collect the precipitate, and dry it at 60℃ to obtain baicalin.

Functions of Scutellaria Baicalensis Extract 85% Baicalin:

Baicalin (Baicalin) is a flavonoid extracted and separated from the root of Scutellaria baicalensis Georgi, which has remarkable biological activity and has antibacterial, diuretic, anti-inflammatory, anti-metamorphosis and spasmolysis effects, and it has strong physiological effects such as anti-cancer reaction. It has played an important role in clinical medicine. Baicalin can also absorb ultraviolet rays, eliminate oxygen free radicals, and inhibit the production of melanin. Therefore, it can be used not only in medicine, but also in cosmetics. It is a good functional cosmetic raw material.

Application of Scutellaria Baicalensis Extract 85% Baicalin:

It is clinically used for acute, chronic persistent and chronic active hepatitis, and can also be used for nephritis, pyelonephritis and allergic diseases. This product has a good effect of lowering ALT. During medication, hepatitis B surface antigen (HBsA, positive titers decreased but not consolidated.