CAS 29070-92-6 Antivirus Powder Poria Cocos Extract Pachymic Acid 5% Polysacchrides 30%

Product Description

Enhance Immune Poria Cocos Extract Powder Pachymic Acid 5% Polysaccharides 30%

Poria cocos is the dry sclerotia of Poria cocos (Schw.) Wolf, a fungus belonging to the family Poria cocos. It is parasitic on the rhizomes of Pinus pine or Pinus massoniana. It is buried 20~30 cm under the soil and multiplies. The inner part of the Poria nucleus is Bai Poria, the outer part is Poria bark, and the sclerotia with pine roots is Poria. It is sweet and light.

Main Active ingredients of Poria Cocos Extract^TM

The main chemical components of Poria cocos extract are: polysaccharides, triterpenoids, , proteins, minerals, etc. Among them, polysaccharides and triterpenoids are the most abundant and active ones, so most of them Separation and identification studies are also carried out for these two types of ingredients. A large number of triterpenoids contained in it have immunomodulatory, anti-tumor, anti-inflammatory, antagonistic aldosterone, induce differentiation of leukemia cell line HL-60 and other good pharmacological activities. As natural active substances, the triterpenoids and polysaccharides in Poria cocos extract have a variety of physiological activities, such as improving the body's immunity, antibacterial, hypoglycemic, and anti-tumor effects.

Application:

1. Immunomodulation

The immunomodulatory function of Poria cocos extravt is currently the most recognized function, and many studies have been conducted on this aspect. For example, using Poria cocos extract for component identification and in vitro animal cell experiments, it was found that 2-N-acetylamino-D-glucose and 6-0-α-D-mannanose-D-glucose contained in it had enhanced The biological activity of immunity can promote the proliferation of mouse lymphocytes, and triterpenoids have the function of two-way immune regulation.

2. Anti-tumor activity

Recent studies have found that polysaccharides in Poria cocos extract powder have a direct effect on tumor cells. They can inhibit tumors by influencing tumor cell signal transduction, inhibiting tumor cell RNA and DNA synthesis, and changing tumor cell growth cycles. However, the unmodified polysaccharide has low biological activity, and its tumor inhibition rate is only 0~3%, while the modified polysaccharide has good anti-tumor activity.

3. Anti-inflammatory

Poria cocos extracts have good anti-inflammatory effects on various inflammations. Most studies have shown that the triterpenoids in Poria cocos are the main components of anti-inflammatory effects, which can achieve anti-inflammatory effects by inhibiting phospholipase (PLA2). 

4. Effects on the urinary system

Chinese medicine believes that Poria has the advantages of diuresis and dampness, which can treat symptoms such as poor urination, swelling. Pachymic acid (PA) was isolated from Poria, and its effect on human prostate tumor cells was studied. It showed that Pachymic acid can maintain the water balance of kidney cells under osmotic pressure and inhibit cell apoptosis under high osmotic pressure.

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