5% Lovastatin Red Yeast Rice Extract Reducing Inflammation

Product Description

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What is red yeast rice?

Red yeast rice is a type of fermented rice that is produced using specific species of mold, Monascus ruber or Monascus purpureus. It’s been used in traditional Chinese medicine for centuries for its powerful health-promoting properties. Red yeast rice contains the compound monacolin K — the same active ingredient found in prescription cholesterol-lowering medications like lovastatin. For this reason, it’s often used as a cost-effective alternative to pricey medications to help reduce cholesterol levels and support heart health. Research has shown other beneficial effects as well, ranging from reduced cancer cell growth to improved blood sugar and insulin levels. Today, red yeast rice is commonly sold as an over-the-counter supplement marketed to help manage cholesterol and improve overall health.

What is Lovastatin?

Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of Aspergillus terreus.1 Originally named Mevinolin, lovastatin belongs to the statin class of medications, which are used to lower the risk of cardiovascular disease and manage abnormal lipid levels by inhibiting the endogenous production of cholesterol in the liver.2 More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,12 which catalyzes the conversion of HMG-CoA to mevalonic acid and is the third step in a sequence of metabolic reactions involved in the production of several compounds involved in lipid metabolism and transport including cholesterol, low-density lipoprotein (LDL) (sometimes referred to as "bad cholesterol"), and very low-density lipoprotein (VLDL). Prescribing of statin medications is considered standard practice following any cardiovascular events and for people with a moderate to high risk of development of CVD, such as those with Type 2 Diabetes. The clear evidence of the benefit of statin use coupled with very minimal side effects or long term effects has resulted in this class becoming one of the most widely prescribed medications in North America.

Benefits:

The potential benefits of red yeast rice include:

improved heart health

reduced risk of metabolic syndrome

decreased inflammation

reduced cancer risk

May promote heart health

Heart disease is a serious condition that affects millions and is estimated to account for 31.5% of deaths around the world. High cholesterol — one of the main risk factors for heart disease — can cause arteries to narrow and stiffen, leading to an increased risk of heart attack and stroke. Red yeast rice is commonly used as a natural remedy to help lower cholesterol levels and promote heart health, and can sometimes have fewer adverse side effects than prescription drugs used to treat high cholesterol. One review of 21 studies found that red yeast rice was effective at reducing levels of total and LDL (bad) cholesterol, as well as triglycerides and blood pressure, when combined with statin drugs. Additionally, the monacolin K may also help improve endothelial function, or the flexibility and adaptability of your blood vessels, which is key to maintaining your vascular and heart health.

May help treat metabolic syndrome

Metabolic syndrome is a cluster of conditions that increase your risk for chronic conditions, such as heart disease, diabetes, and stroke. Some of the criteria for metabolic syndrome include high blood pressure, excess body fat, increased blood sugar, and alterations in cholesterol or triglyceride levels. Several studies have found that red yeast rice may help treat some of these risk factors and could be used as a natural treatment to aid in their prevention.

One of its most well-documented effects is its ability to lower cholesterol. Research shows that it can effectively reduce both total and LDL (bad) cholesterol levels. Another small, 18-week study found that a supplement containing red yeast rice was able to reduce blood sugar, insulin levels, and systolic blood pressure (the top number of a reading) in people with metabolic syndrome. Plus, an 8-week study looked at the effects of red yeast rice on mice fed a high fat diet compared with a control group. It found that red yeast rice was able to prevent increases in cholesterol levels and body weight.

Could reduce inflammation

Inflammation is a normal immune response designed to protect your body against acute infections and foreign invaders. However, sustained inflammation is thought to contribute to chronic conditions like diabetes, cancer, and heart disease. Studies show that supplementing with red yeast rice may help reduce inflammation and promote better health in the long term. For example, a study in 50 people with metabolic syndrome showed that taking a supplement containing red yeast rice and olive extract for 8 weeks reduced levels of oxidative stress — a key cause of chronic inflammation — by up to 20 percent. Similarly, one study found that giving red yeast extract to rats with kidney damage reduced levels of specific proteins involved in inflammation in the body.

May have anticancer properties

Although current research is limited to animal and test-tube studies, some evidence suggests that red yeast rice may help reduce the growth and spread of cancer cells. One study found that giving mice with prostate cancer red yeast rice powder significantly decreased tumor volume compared with a control group. However, more research is needed to evaluate the effects of red yeast rice on other types of cancer in humans. Specifically, further studies should be done to determine how the potential anticancer effects of red yeast rice may affect the general population.

Application:

1. Condiment(braise meat,preserved beancurd,jam);

2. Food(meat,juice,drink,wine,beverage,candy, noodle,health food, cake,sanitaniam vinegar and etc.);

3. Medicine(Medicine colorant, Medicine ingredients etc);