Anti Cancer Cordyceps Extract Powder CAS 73-03-0 Cordycepin Adenosine 1% 8% 98%

Product Description

Anti Cancer Cordyceps Extract Cordycepin Adenosine 1% 8% 98%

The content of adenosine in Cordyceps cannot represent the unique medicinal and health-care value of Cordyceps. Therefore, the use of adenosine as the only quality indicator is to "depreciate" the special value of Cordyceps and cannot reflect the unique mystery of Cordyceps for disease prevention and treatment. Among many cordyceps, it can produce the most unique and representative component of cordycepin.

Cordyceps extract cordycepin is also called cordycepin, cordycepin, cordycepin, alias 3'-deoxyadenosine, chemical formula C10H13N5O3, is the first nucleoside antibiotic isolated from fungi.

Phsycal Proproties of HDPharma Codcyceps Extract™

In the 1950s, wild Cordyceps militaris was discovered in China. Studies have confirmed that its ingredients are far more effective than wild Cordyceps, hence the name Cordyceps militaris. In 1951, German scientist Cunningham and others first discovered the core component of Cordyceps militaris, "cordyceps extract" It has a variety of pharmacological activities such as antibacterial, anti-inflammatory, antiviral, anti-tumor and immunomodulation. In the following decades, academia has carried out a large number of researches on cordyceps extract cordycepin; in 1997, the United States has extracted cordyceps Cordycepin is used in Phase III clinical trials to treat patients with acute pre-B and pre-T lymphocytic leukemia; in 2017, Professor Wang Chengshu of the Chinese Academy of Sciences published the latest research results on cordycepin, an extract of cordycepin, in Cell Chemical Biology online : This study completely analyzed the biosynthesis mechanism of Cordyceps extract cordycepin in Cordyceps militaris. At the same time, it was first discovered that Cordyceps militaris can synthesize anti-cancer drug-pentostatin, which is used to protect the synthesized cordyceps The structural stability of the extract cordycepin.
Research results show that Cordyceps extract has biological activities such as lung and kidney protection, anti-three high, anti-tumor, neuroprotective, anti-inflammatory, anti-oxidant, and immune regulation. Therefore, cordycepin, an extract of cordyceps, has attracted much attention from scholars in the fields of anti-aging, health care, and new drug development.

What is the function of Cordyceps Extract™?

Lung and kidney protection

• Cordyceps extract cordycepin can effectively reduce lung fibrosis, improve lung tissue structure and fibrotic pathological changes.

Anti-three high effects

• Cordyceps extract cordycepin has a good effect on lowering blood lipids, and it also affects fat production while lowering blood lipids.

Anti-tumor effect

• Cordyceps extract may inhibit the proliferation of cancer cells by regulating p85/AKT or GSK3β-r.
• Cordyceps extract cordycepin has an inhibitory effect on the growth of A549 lung cancer and H358 lung cancer cells.
• Cordyceps extract can activate the Caspases of lung cancer cells and further cause lung cancer cells to undergo apoptosis.
• Cordyceps extract cordycepin can activate the PLC/PKC signal transduction pathway in cells, promote the production of in MA-10 cells, and then cause cell apoptosis.
• Research on the anti-cancer mechanism of cordycepin extract on CGTHW-2 thyroid cancer cell lines found that cordycepin extract cordycepin induces an increase in intracellular calcium levels and activates calpain, which in turn triggers Caspase7 activation and PARP lysis.
• Cordyceps extract cordycepin is a non-mutagenic and non-toxic compound, which has potential anti-proliferation and anti-migration effects on A549 lung cancer cells.
• Cordyceps extract combined with cisplatin can activate the activity of exogenous and endogenous caspases in human oral cancer cell lines, and promote the expression of MAPK pathway to promote cell apoptosis.
• Cordyceps extract cordycepin can inhibit the apoptosis of PC12 cells induced by rotenone and has a potential protective effect. The drug concentration between 1～102μmol·L-1 has a good inhibitory effect on the proliferation of PC12 cells.

Neuroprotection and regulation

• Cordyceps extract cordycepin has an important neuroprotective effect in hypoxia or ischemic injury. During the study of the electrophysiological mechanism of cordycepin extract cordycepin to protect ischemia and hypoxia damage, it was found that cordycepin cordycepin (80μmol/L) can significantly delay hypoxia-induced membrane depolarization and prolong the spontaneous action potential (AP). ) The ability to issue delays the occurrence of rapid depolarization. In addition, Cordyceps extract also delays the decrease in induced AP amplitude caused by hypoxia. Studies have shown that Cordyceps extract has an important neuroprotective effect against hypoxic damage by improving the electrophysiological function of neurons.

Anti-inflammatory and antibacterial effects

• Cordyceps extract cordycepin has a wide range of activities against a variety of pathogenic microorganisms. Cordyceps extract cordycepin has the effect of inhibiting the reverse transcriptase activity of human immunodeficiency virus (type) and preventing its infiltration. Cordyceps extract itself has no inhibitory effect on Staphylococcusaureus and Candidaalbican, and the chemically modified Cordyceps extract shows certain antibacterial activity against them. Due to the short half-life and short action time of cordycepin extract cordycepin, researchers can prepare cordycepin cordycepin extract into a sustained-release preparation to prolong the action time in the body and improve the maintenance of efficacy in multiple and continuous administrations the way.

Improve sleep

• Cordyceps extract reduces the sleep-wake cycle by regulating the hypothalamus, and increases non-rapid eye movement (NREM) sleep by increasing non-specific adrenergic and adrenergic receptors.

Cordyceps extract cordycepin also has pharmacological activities such as hypoglycemic and gonadotrophic development.

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