Skin Care Ingredient Centella Asiatica Extract Asiaticoside 10% CAS 16830-15-2 HPLC

Product Description

Skin-care Ingredient Centella Asiatica Extract Asiaticoside 10% CAS.16830-15-2 HPLC

Products description:

Centella Asiatica is a plant that is known as Indian pennywort, Asiatic pennywort, Gotu kola, Brahmi, or Tiger Grass. It’s native to Asia and grows in the Indian subcontinent, Southeast Asia, as well as Southeastern US and other regions. Centella has been used in culinary in many Asian countries and as a medicinal herb in traditional medicine to heal minor wounds due to its healing properties and treat some disorders and skin conditions such as psoriasis, eczema, and varicose ulcers, etc.

Centella Asiatica can increase the resistance of the skin epidermis, has anti-inflammatory, sedative, detoxifying, and swelling effects, imparts elasticity to the skin, strengthens the skin's softness, and can delay aging. Centella Asiatica, with its excellent star effect, has accumulated a lot and has almost become the "magic oil" of snow skin care in the beauty and skin care industry.

pharmacological action

Centella Asiatica is the dry whole grass or rooted whole grass of Centella Asiatica (L)Urban, also known as Lei Gong Root, Horseshoe Grass, and Fallen. It can be harvested all year round and is rich in resources. It grows in Southeast Asia, Australia, South Africa, and the Central African tropics have a long history of application in the field of medicine in many countries. Centella Asiatica is cold in nature and bitter in taste. It has the effects of clearing away heat and dampness, detoxifying, and reducing swelling. It is mainly used for damp-heat jaundice, heatstroke diarrhea, carbuncle sores, and traumatic injuries. Asiaticoside belongs to pentacyclic triterpenoids, and has various pharmacological effects such as anti-ulcer, promoting wound healing, anti-tumor, anti-inflammatory, and immune regulation. It is currently mainly used for the treatment of scleroderma and skin wounds and burns.

Mechanism

Madecassoside can act on the nuclei of fibroblasts to reduce the mitotic phase, and the nucleoli become smaller or absent. With the increase of the drug concentration, the synthesis of intracellular DNA decreases, cell growth is inhibited, and the inhibition rate can reach up to 73%. %, suggesting that the mechanism of Asiaticoside is to block the proliferation of fibroblasts, thereby reducing the synthesis of collagen and preventing scarring.

Application

Asiaticoside is the main component of the medicinal material Centella Asiatica. The mixture of Asiaticoside A and Asiaticoside B has pharmacological effects such as promoting wound healing, anti-wrinkle, anti-inflammatory, anti-depression, and promoting intelligence. Comparing the pharmacological effects of Asiaticoside in promoting wound healing and treating scars, it can be found that the pharmacological effects of Asiaticoside A and Asiaticoside B may play a major role in the anti-inflammatory, antidepressant, and intellectual promotion of total Asiaticoside. effect.

Chemical properties

White crystalline powder, easily soluble in water and ethanol, insoluble in ether and chloroform, derived from Centella Asiatica.

Purpose

Promote wound healing, stimulate granulation growth, and treat various skin diseases.